Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization
Pulmonary fibrosis is a devastating lung disease without effective treatment options.Sphingosine-1-phosphate receptor 3 (S1pr3), a receptor for the lipid nandos plates for sale signaling molecule sphingosine-1-phosphate, has been shown to mediate the development of pulmonary fibrosis, although the underlying mechanism is not fully understood.Here,